دانلود فایل پاورپوینت عوارض جانبی داروهای گوارشی

بخشی از پاورپوینت

اسلاید 1 :

گروههای دارویی

H2- بلوکرها    آنتی کولینرژیکها

مهار کننده های پمپ پروتون  آنتی اسیدها

آنتی کولینرژیکها  ملین ها

داروهای پروکینتیک  کلپرمین

اسلاید 2 :

Histamine H2-Antagonists
H2- Blockers

اسلاید 3 :

مصرف از راه خوراكي،  عدم عارضه جانبي مهم

به جز سايمتيدين:

ژينكوماستي (دوز بالا)

كاهش قواي جنسي در مردان (تغيير در متابوليسم

استروژن)، مهار آنزيمهاي سيتوكروم

اسلاید 4 :

Unlike cimetidine, ranitidine does not seem to affect cytochrome P450 to any great extent, and therefore is considered to have little effect on the metabolism of other drugs

اسلاید 5 :

Ranitidine

Adverse Effects (mainly by parentral forms)

Effects on the cardiovascular system:. Bradycardia, AV block and  cardiac arrest has been reported .

Also a +ve inotropic effect.

Effects on the endocrine system: gynaecomastia, loss of libido, and impotence  less than cimetidine   

اسلاید 6 :

….. Ranitidine

Effects on the nervous system: confusion, loss of color vision, aggressiveness, lethargy,somnolence, disorientation, depression, hallucinations and severe headache, 

Effects on the liver:hepatotoxicity

اسلاید 7 :

Famotidine

Adverse Effects

Effects on the cardiovascular system: 40 mg daily by mouth reduced cardiac output and stroke volume. Also bradycardia and AV block has been reported

Effects on the endocrine system: transient hyperprolactinaemia and glactorrhoea

Effects on the nervous system: convulsions and mental deterioration in elderly patients with renal failure, 

اسلاید 8 :

Nizatidine

Unlike cimetidine, nizatidine does not seem to affect cytochrome P450 to any great extent, and therefore is considered to have little effect on the metabolism of other drugs

اسلاید 9 :

Nizatidine

Adverse Effects

Effects on the cardiovascular system: has been reported to reduce heart rate, also tachycardia, bradycardia, orthostatic hypotension and syncope have been reported rarely with rapid intravenous injection

Some patients taking nizatidine may experience excessive sweating and urticaria; anaemia may also occur

اسلاید 10 :

…..  Nizatidine

Nizatidine is considered to have little or no anti-androgenic activity although there are isolated reports of gynaecomastia and  impotence